Melorheostosis is a rare and progressive condition that affects bone formation in various areas of the skeleton. In unusual instances, the disease also affects the spine. Although it impacts soft tissue formation, it has no relation to cancer. Melorheostosis can develop in both children and adults, with equal prevalence in men and women. The exact cause of the syndrome is still unknown. However, investigation of some cases points to a genetic link. To date, no standard protocol has been effective in producing positive improvements across all cases. At the time of this writing, doctors have been able to identify roughly 400 cases.
Symptoms of Melorheostosis include:
- Irregular cortical bone thickening
- Shortened tendons and ligaments
- Joint tenderness and swelling, particularly in the arms and legs
- Nerve compression due to bone lesions
- Limited range of motion
- Stiffness and pain
Although the causes of Melorheostosis are presently unknown, the most likely culprit is thought to be a specific gene mutation. At least in a small number of affected individuals. Unfortunately, there is no further research showing any other genetic association.
X-ray imaging is the diagnostic tool of choice for confirming Melorheostosis, as MRIs often receive a poor signal. Bone scans also demonstrate positive result. The x-ray will often show thickened bone that looks much like dripping candle wax.
Therapy for Melorheostosis focuses on relieving symptoms. Treatment options are presently limited. The reason is because there is none that has produced effective results for the majority of people with the condition. Physical and occupational therapy for strengthening and stretching, along with pain medication and hydrotherapy may be beneficial. Medication to aid in bone restructuring may also be prescribed.
Pain control is tricky, with steroids or non-steroidal anti-inflammatory drugs providing relief mainly in the early stages of the condition. On rare occasions, narcotics may be necessary.
Do you have chronic stiffness and pain in your back or neck? Schedule an appointment with the Spine Center of Texas or to learn about treatment options. We have offices in New Braunfels or Seguin, and our spine doctors have years of experience.
